Imagine what would happen if our kidneys stopped working, if our bodies were no longer able to filter toxins. Unfortunately, this is reality for people living with polycystic kidney disease (PKD).
In PKD, cysts appear on the kidneys. The cysts interfere with normal kidney function, causing (among other symptoms) increased blood pressure and a build-up of toxins. The abnormal cyst formation is due to a mutation in the polycystin producing genes (PKD1 and PKD2). In some forms of the disease, the mutations are passed through each generation, making PKD the most prevalent hereditary disease in the world.
There is no long term cure for PKD. Current therapies can only ease the symptoms. Over the last year and a half, however, I have been trialing the use of new drugs which might delay cystic growth and be a potential treatment for PKD.